Bleeding and thrombosis in childhood cancer
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چکیده
Defects of hemostasis in patients with cancer have been first described by Trousseau in 1865, and Morrison studied altered coagulation in patients with malignancy as early as 1932. The first described abnormality of hemostasis in malignancy was that of hypercoagulability and thrombosis and the first large survey of blood changes in cancer patients showed accelerated bleeding times in over 60% of patients studied. This presentation discusses thrombotic and hemorrhagic disorders that occur in children with solid tumors and hematological malignancies.
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